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Search Results for " calcium signaling "

20

Compounds

Cat No. Product Name Synonyms Targets
T8452 Dantrolene Others
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
T28073 MLS1547 MLS000051547,MLS 1547,MLS-1547 Dopamine Receptor
MLS1547 (MLS000051547) is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assa...
T6245 BAPTA-AM BAPTA/AM Potassium Channel
BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM). BAPTA-AM has a 105-fold higher affinity for Ca2+ than for Mg2+, and can be used for...
T27499 GSK-A1 HCV Protease , PI4K
GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.
T14871 Carboxyamidotriazole Orotate L-651582 Orotate,CAI Orotate Calcium Channel
Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the o...
T124384 Jasmonic acid (-)-Jasmonic acid
Jasmonic acid (JA) is a phytohormone and plant growth regulator involved in plant defense and growth and development.Jasmonic acid plays an important role in signaling, inducing the MAP kinase cascade pathway and calcium...
T5120 Rhamnose 6-Deoxyhexopyranose,6-Deoxy-L-mannose,alpha-L-Rhamnose Calcium Channel , Endogenous Metabolite
Addition of the Rhamnose (6-Deoxy-L-mannose)-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, ind...
T2170 SKF-96365 hydrochloride SKF96365 Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha...
TP1565L1 Foxy-5 Ammonium Salt Foxy-5 Ammonium Salt(881188-51-8 Free base) Wnt/beta-catenin
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in...
T3929 Kaurenoic acid Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid Others
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...
T11363 Ganoderic acid F Others
Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si...
T14872 Carboxyamidotriazole CAI,L-651582 Calcium Channel
Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects.
T83950 ARN 11391
ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion signaling by directly targeting ITPR1. Furthermore, ARN 1139...
T21387 Nafoxidine HCl(1845-11-0 Free base) PNU-0011100,PNU0011100,CP5600,CP 5600,CP-5600,PNU 0011100,Nafoxidine HCl
Nafoxidine is a partial estrogen antagonist. It inhibits angiogenesis in some tissues by blocking the effects of VEGF and FGF; paradoxically, it may enhance angiogenesis in uterine tissue. Nafoxidine also induces calcium...
T37803 8-bromo-Cyclic ADP-Ribose (sodium salt)
Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, w...
T76663 PTH-Related Protein (1-40) (human, mouse, rat)
pTH-Related Protein (1-40) (human, mouse, rat) enhances calcium absorption in rat intestinal cells by activating the PTHR1 receptor and the PKCα/β signaling pathways. This compound also increases the expression of the pa...
T18989 Fluo-3AM Fluo-3-pentaacetoxymethyl ester Others
Fluo-3AM is a calcium indicator that exhibits an increase in fluorescence upon binding Ca2+. It is used to image the spatial dynamics of Ca2+ signaling in flow cytometry experiments.
T82538 DM-Nitrophen tertasodium
DM-Nitrophen tertasodium acts as a calcium (Ca 2+) cage, releasing Ca 2+ when cleaved by near-ultraviolet light illumination, and is utilized in the study of Ca 2+ signaling.
T36838 (R)-Bromoenol lactone
The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily...
TP1296 Foxy-5 TFA(881188-51-8 free base) Foxy-5 (TFA)
Foxy-5 is a peptide that mimics the WNT5A protein and is expected to reduce the mobility of the cancer cells. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the mig...

Compounds

Dantrolene
T8452
Synonym:
Target: Others
MLS1547
T28073
Synonym: MLS000051547,MLS 1547,MLS-1547
Target: Dopamine Receptor
BAPTA-AM
T6245
Synonym: BAPTA/AM
Target: Potassium Channel
GSK-A1
T27499
Synonym:
Target: HCV Protease, PI4K
Carboxyamidotriazole Orotate
T14871
Synonym: L-651582 Orotate,CAI Orotate
Target: Calcium Channel
Jasmonic acid
T124384
Synonym: (-)-Jasmonic acid
Target:
Rhamnose
T5120
Synonym: 6-Deoxyhexopyranose,6-Deoxy-L-mannose,alpha-L-Rhamnose
Target: Calcium Channel, Endogenous Metabolite
SKF-96365 hydrochloride
T2170
Synonym: SKF96365
Target: Apoptosis, Potassium Channel, Calcium Channel, TRP/TRPV Channel, Autophagy
Foxy-5 Ammonium Salt
TP1565L1
Synonym: Foxy-5 Ammonium Salt(881188-51-8 Free base)
Target: Wnt/beta-catenin
Kaurenoic acid
T3929
Synonym: Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid
Target: Others
Ganoderic acid F
T11363
Synonym:
Target: Others
Carboxyamidotriazole
T14872
Synonym: CAI,L-651582
Target: Calcium Channel
ARN 11391
T83950
Synonym:
Target:
Nafoxidine HCl(1845-11-0 Free base)
T21387
Synonym: PNU-0011100,PNU0011100,CP5600,CP 5600,CP-5600,PNU 0011100,Nafoxidine HCl
Target:
8-bromo-Cyclic ADP-Ribose (sodium salt)
T37803
Synonym:
Target:
pTH-Related Protein (1-40) (human, mouse, rat)
T76663
Synonym:
Target:
Fluo-3AM
T18989
Synonym: Fluo-3-pentaacetoxymethyl ester
Target: Others
DM-Nitrophen tertasodium
T82538
Synonym:
Target:
(R)-Bromoenol lactone
T36838
Synonym:
Target:
Foxy-5 TFA(881188-51-8 free base)
TP1296
Synonym: Foxy-5 (TFA)
Target:
1 2
TargetMol